depression is now the second leading cause of disease burden

Question:

According to the 2010 Global Burden of Disease study, depression is now the second leading cause of disease burden (as cited in Ferrari et al., 2013), whilst WHO (2012) declares depression to be the leading cause of disability worldwide. There is a distinct pattern along gender lines when it comes to prevalence rates of depression: unipolar depression is twice as common in women (WHO, n.d.).

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